30th Anniversary Mizutani Foundation for Glycoscience

RESERCH REPORTS

2017-2021

2017

Innovation of the glycosidation reaction of sialic acid

Hiromune Ando

Institute for Glyco-core Research (iGCORE), Gifu University, Japan

Unraveling of regulation mechanisms of receptor activity by gangliosides

Kenichi G. N. Suzuki

Gifu University, Institute for Glyco-core Research

Creation of carbohydrate derived epigenetic controlling molecules

¹Yukishige Ito

²Kunio Shiota
¹Osaka University and RIKEN, ²Emeritus Professor, The University of Tokyo

Gut microbiota-sensitive O-GlcNAc signaling protects intestinal inflammation

Development of a nondestructive system to analyze disease-associated glycomes

Hiroaki Tateno

Cellular and Molecular Biotechnology Research Institute, National Institute of Advanced Industrial Science and Technology

2018

Regulation of cytokinesis and exosome formation by chondroitin sulfate

Hiroshi Kitagawa

Collaborators: Yuko Naito-Matsui, Ban Sato, and Satomi Nadanaka
Kobe Pharmaceutical University

Effects of environmental factors on the quantity and quality of polysialic acid in the brain

Chihiro Sato

Bioscience and Biotechnology Center, Department of Bioagricultural Sciences, Institute for Glyco-Core Research, Nagoya University

Action mechanism of bio-active sugar chain AMOR

Tetsuya Higashiyama

Institute of Transformative Bio-Molecules, Nagoya University (Current Institution: Graduate School of Science, The University of Tokyo)

In vivo genome wide dynamics of O-GlcNAcylated chromatin-associated proteins brain

Potential impact of perineuronal net on the pathogenesis of Schizophrenia

Toshitaka Oohashi

Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

2019

Environmental and pathogenic triggers of intestinal inflammatory disease

^1-3 Won Ho Yang, ^1,3 Douglas M. Heithoff, ^1-3 Peter V. Aziz, ⁴ Markus Sperandio, ⁵ Victor Nizet, ^1,3 Michael J. Mahan, and ^1-3,6Jamey D. Marth
¹Center for Nanomedicine; ²SBP Medical Discovery Institute; ³ Department of Molecular, Cellular, and Developmental Biology, University of California Santa Barbara; ⁴ Walter Brendel Center for Experimental Medicine, Ludwig Maximilian University, Munich, Germany; ⁵ Department of Pediatrics and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, Dentistry and Pharmaceutical Sciences

Clarification of a novel degradation pathway for O-Man glycans in S. cerevisiae

Tadashi Suzuki

RIKEN Cluster for Pioneering Research (CPR)

Glycolipids generated by metabolic crosstalk between sphingolipid and sterol

Yoshio Hirabayashi

Riken Cluster for Pioneering Research and Juntendo University, Institute for Environmental and Gender-Specific Medicine

Molecular mechanism of glucosylation of the dolichol-linked N-glycan precursor

Anant K. Menon

Weill Cornell Medical College, Department of Biochemistry

Development of neoglycobiologics using transglycosylation technology

Kohji Itoh

Department of Medicinal Biotechnology, Institute for Medicinal Research, Graduate School of Pharmaceutical Sciences, Tokushima University

2020

The novel cell surface hyaluronidase TMEM2 in tumor cell invasion

Yu Yamaguchi

Sanford Burnham Prebys Medical Discovery Institute

A novel structure of GPI anchored proteins and its physiological role

Yoshiko Murakami

Research Institute for Microbial Diseases, Osaka University

Reversal of HIV latency by Galectin-9 in vivo

Mohamed Abdel-Mohsen

Zhe Yuan, Leila B. Giron, Toshiro Niki, Lishomwa C. Ndhlovu,Luis, J Montaner
The Wistar Institute, Philadelphia, PA, USA

Development of an umpolung glycosylation for the synthesis of α- or β-linked O-2-deoxyglycosides

Seth B. Herzon

¹Kevin M. Hoang, 1Nicholas R. Lees, ¹Xiaoying Zheng, and ^1,2Seth B. Herzon
¹Department of Chemistry, Yale University. ²Departments of Pharmacology and Therapeutic Radiology, Yale School of Medicine

Ganglioside biosynthetic diseases

Frances Platt

¹David Priestman, ²Emma Baple, ²Andrew Crosby and ¹Prof Frances Platt
¹Department of Pharmacology, University of Oxford, UK, ²University of Exeter Medical school, Exeter, UK

2021

Therapeutic in vivo synthetic chemistry by glycosylated artificial metalloenzyme

Katsunori Tanaka

¹Tsung-che Chang and ^1,2Katsunori Tanaka
¹Biofunctional Synthetic Chemistry Laboratory, RIKEN Cluster for pioneering research, ²Department of Chemical Science and Engineering, School of Materials and Chemical Technology, Tokyo Institute of technology

Development of novel mechanism-based inhibitors for glycohydrolases

To be published at a later date.

Go Hirai

Graduate School of Pharmaceutical Sciences, Kyushu University

DIGITAL-BOOK

Messages for the 30th Anniversary

Greetings Ken Mizutani (Chairperson, the Board of Directors)

Message Kunihiko Suzuki (Board of Directors)

Message Tamao Endo (Board of Directors, Chairperson, Selection Committee)

30th Anniversary Commemorative Symposium

Program

Special Lecture Christina M. Woo

Invited Lecture Yoshihiro Kawaoka

Special Lecture Yasuhiro Kajihara

Invited Lecture Kenji Kadomatsu

Mizutani Grant for Glycoscience Research

Application guidelines for research grant

Statistics

Grant awardees and titles (2018-2022)

List of Awardees (1993-2022)

Research Reports - Results and Perspectives -

Selected abstracts of the research grant projects (2017-2021)

Support for Glycoscience Meetings

Application guidelines

List of the International Exchanges and Glycoscience Meetings

Outline of Mizutani Foundation for Glycoscience

Outline of the Foundation

Board members

Past board members

Aim of the Foundation

30th Anniversary Mizutani Foundation for Glycoscience | RESERCH REPORTS